Abstract: Behcet’s Disease (BD) is a multisystemic disease with a peculiar distribution in the world. The disease is specially seen in the countries bordering the ancient SILK ROAD specially Japan, China, Korea, Iran, and Turkey. The majority of reports on BD are on hospital based patients. Others are either local based patients or epidemilogical studies on a small area. The only two nationwide analysis of BD is from Japan and ...
Abstract: INTRODUCTION: Behcet’s Disease (BD) is classified among vasculitides, but its clinical picture is very distinctive and can be easily differentiated from the others. BD was originally seen along the Silk Road, but due to immigrations it is now seen everywhere in the world. There are many reports on clinical manifestations of BD from different parts of the world. The majority are case series except two nationwide surveys, one from Iran1, ...
Abstract: Introduction: We previously reported that ankylosing spondylitis (AS) was associated with Behcet's disease (BD) in Iranian patients. This study was designed to evaluate the features of AS in BD (ASBD) and compare them with the AS in normal population (ASN). Materials and Methods: Among 4700 BD patients, 73 ASBD were found and were compared with a cohort of 180 ASN. Seventy out of 73 ASBD met the European Spondyloarthropathy Study Group ...
Abstract: Background: The purpose of this study was to evaluate the difference between oral aphthae in Behcet’s Disease (BD) and recurrent aphthous stomatitis (RAS). Methods: In a prospective study 56 cases of BD and 133 RAS were evaluated consecutively. Sex, age of onset, frequency of aphthous lesions, their duration and their mean number at each attack, pathergy test, HLA-B5, HLA-B51 and HLA-B27 were evaluated in both groups. Comparison was made by Student ...
Abstract: Objective: SLE is an autoimmune disease. The mortality rate and causes are different in the various countries. The present study is done to find out the causes of mortality in the SLE patients in Iran. Methods: This study was retrospective according to medical records of patients who were referred to Rheumatology polyclinic, admitted in Rheumatology ward, ICU, Gynecology and Nephrology wards of Shariati hospital during 10 years, from 1991-2001. Results: Of 2021 ...
Abstract: Introduction: Pyoderma gangrenosum (PG) like lesion is a Behcet’s disease (BD) skin lesion, which is seen very exceptionally. We report here 2 cases with unusual severe and extensive skin lesions, having an intensive hypersensitivity to needle injection, inducing new lesions. Cases report: The first case is a 42 years old man with a history of 5 years recurrent bipolar aphthosis, skin pustulosis, ocular lesions, and articular involvement. After ...
Abstract: Introduction: Ocular manifestations are seen more frequently in men than women (62% men, 49% women). The difference is statistically significant (p
Abstract: Introduction: The natural course of eye lesions is well known, leading to sever loss of vision or blindness. The cumulative nature of eye lesions during successive attacks, leads to gradual loss of visual acuity (VA). The aim of this study was to evaluate the effect of the delay in aggressive treatment on the VA and its long-term outcome. Materials and Methods: All Behcet’s patients of the treatment registry (1009 ...
Abstract: Ocular manifestations like other manifestations of Behcet’s Disease (BD) progress by repetitive attacks followed by remission. However, the remission is much slower in posterior uveitis, and practically absent in retinal vasculitis. Usually the healing process do not complete before the next attack. Therefore, lesions will accumulate during successive attacks and lead to severe loss of vision or blindness. An inflammatory index and visual acuity has to be calculated for each ...
Abstract: Introduction: It is known from long date that some manifestations are seen more frequently in men than women and in some of them the difference may be statistically significant. The aim of this study was to address that issue and to find if a statistical difference was of any clinical relevance or significance Materials and Methods: All patients of the BD registry (4717 at January 20, 2002) entered the ...