کتاب‌خانه مجازی

EXPERIENCE IN IRAN WITH SPECIAL REFERENCE TO BEHCETS DISEASE (BD).

Abstract: Pattern of Rheumatic Diseases in Iran: They have the same frequency and the same pattern as in Western countries. A study from 1993 demonstrated a prevalence of 32.6% among adults (31.4% in the USA, Cunningham 1984). Inflammatory disorders counted for 11% of all rheumatic diseases. The ratio of RA to AS was 8/1 (7/1 in USA), and SLE to Scleroderma 3.5/1 (3.6/1 in USA). Psoriatic arthritis and Reiter's syndrome were rare in Iran while Behcet's disease had much higher incidence. Osteoarthritis counted for 32%, low back pain 27%, and soft tissue rheumatism for 16% of all rheumatic complaints. Epidemiology of BD: It is seen more frequently in Iran than in Western countries. From 1975 to 2000, 4413 patients were registered in our database. The annual incidence during the last 11 years varied between 250 and 350 new patients (population: 60 millions). The estimated prevalence is 1.5 BD for 10,000 inhabitants. BD is seen more frequently in northwestern part of Iran. The disease is twice more frequent in Turk ethnic group than in Caucasians. The male to female ratio was 1.17/1. The mean age at the onset was 26 ± 9.6 SD, confidence interval (CI) at 95% = 0.3. Clinical Manifestations were: Mucous membrane 97% of patients (oral apotheosis 96% and genital potheosis 65%), skin manifestations 72% (pseudofolliculitis 64%, erythema nodosum 23%), ocular lesions 56% (anterior uveitis 42%, posterior uveitis 45%, retinal vasculitis 31%), joint manifestations 36% (arthralgia 16%, mono-arthritis 8%, polyarthritis 18%, ankylosing spondylitis 1.5%), neurological manifestations 3.3% (central 3.1%, peripheral 0.2%), gastro-intestinal manifestations 8%, epididymitis 6%, phlebitis 7%, large vein thrombosis 1%, arterial thrombosis 3 cases, aneurysm 6 cases, pulmonary manifestation 0.7%, and cardiac manifestations 0.6%. T39 EXPERIENCE IN IRAN WITH SPECIAL REFERENCE TO BEHCET'S DISEASE (BD). Davatchi F Shahram F, Chams C, Chains H, Nadji A, Jamshidi AR, Akbarian M, Gharibdoost F. Rheumatology Research Center, Tehran University for Medical Sciences. Tehran, Iran. Pattern of Rheumatic Diseases in Iran: They have the same frequency and the same pattern as in Western countries. A study from 1993 demonstrated a prevalence of 32.6% among adults (31.4% in the USA, Cunningham 1984). Inflammatory disorders counted for 11% of all rheumatic diseases. The ratio of RA to AS i%-as 8/1 (7/1 in USA), and SLE to Scleroderma 3.3/1 (3.6/1 in USA). Psoriatic arthritis and Reiter's syndrome were rare in Iran while Behcet's disease had much higher incidence. Osteoarthritis counted for 32%, low back pain 27%, and soft tissue rheumatism for 16% of all r:ieumatic complaints. Epidemiologv• of BD: It is seen more frequently in Iran than in Western countries. From 1975 to 2000, 4413 patients were registered in our database. The annual incidence during the last 11 years varied between 250 and 350 new patients (population: 60 millions). The estimated prevalence is 1.5 BD for 10,000 inhabitants. BD is seen more frequently in northwestern part of Iran. The disease is twice more frequent in Turk ethnic group than in Caucasians. The male to female ratio was 1.17/1. The mean age at the onset was 26 ± 9.6 SD, confidence interval (CI) at 95% = 0.3. Clinical Manifestations were: Mucous membrane 97% of patients (oral aphthosis 96% and genital aphthosis 65%), skin manifestations 72% (pseudofolliculitis 64%, erythema nodosum 23%), ocular lesions 56% (anterior uveitis 42%, posterior uveitis 45°,%, retinal vasculitis 31%), joint manifestations 36% (arthralgia 16%, mono-arthritis 8%, polyarthritis 18%, ankylosing spondylitis l.S%), neurological manifestations 3.3% (central 3.1°,%, peripheral 0.2%), gastro-intestinal manifestations 8°,%, epididymitis 6%, phlebitis 7%, large vein thrombosis 1%, arterial thrombosis 3 cases, aneurysm 6 cases, pulmonary manifestations 0.7%, and cardiac manifestations 0.6%.