Abstract: Ophthalmologic lesions, specially posterior uveitis (PU) and retinal vasculitis (RV), are the leading cause of morbidity in BD. Despite many problems encountered in their treatment, it is accepted today that cytotoxic drugs are the preferred choice. Cyclosporin (CYC) is another effective drug and Corticosteroids only have a temporary effect on inflammatory state. Other conventional drugs (like Colchicine, levamisole and etc.) has no place in the treatment of these lesions. We present ...
Abstract: Articular involvement was present in 43% (CI-1.9) of patients with BD in Iran. Inflammatory arthralgia with morning stiffness was seen in 22% (CI = 1.6); Oligoarthritis, the most characteristic form mainly involving the large joints, was present in 20% (CI = 1.1); and monoarthritis mainly in the knee joints in 11 % (CI = 1.5). All these manifestations are usually transient with a tendency to relapse, but not as often ...
Abstract: From the most ancient time, mechanical disorders of the spine were one of the major concerns of mankind. Perhaps no other disease has initiated so many different treatments, during the history of Medicine. All these methods are said to be efficient, if not the most efficient, by their promoter. It is interesting to note that each of these methods acts upon a different mechanism. It is therefore Understandable if one asks ...
Abstract: It is difficult to define what exactly is intractable RA. Intractable RA may be defined as a patient. resistant to standard treatment. The difficult point is how to define the standard treatment. Shall we say intractable disease to a patient resistant to single DMARD and an NSAID? Or shall we say intractabIe disease to a patient resistant to a combination of DMARD with low dose steroid and associated NSAID who ...
Abstract: From 1969 to 1993 six major sets of diagnosis criteria were proposed for BD. The analysis of sensitivity, specificity and the accuracy was done on 2632 BD patients and 1916 control patients. A Confidence Interval (CI) at 95% was calculated for each result. Sensitivity: Mason & Barnes 70.9% ± 1.7, O'Duffy 77% ± 1.6, International 84.5% ± 1.4, Dilsen 89.4% + 1.2, Japan 90.8% ± 1.1, Iran 95.6 ± 0.8 ...
Abstract: Rheumatoid arthritis is a common disease occurring in 1% of the population. Therefore it is not unusual to see a rheumatoid arthritis patient who needs anticoagulation therapy for another reason than her or his RA. Anticoagulation therapy has no contra-indication for RA itself. However many drugs used in RA may interfere with anticoagulant drugs. The major problem arises from NSAIDs, particularly salicylate. These drugs have a synergistic effect on coumadin ...