Abstract: Objective: To assess the course of maternal disease and outcome of pregnancy in patients with systemic lupus erythematosus (SLE). Patients and Methods: One hundred SLE patients who carried out 128 pregnancies were studied retrospectively. These patients were followed in lupus unit every one to two months by the rheumatologist and obstetrician team throughout pregnancy. Some patients were given prophylactic low-dose Prednisolone. Lupus flares were treated by increasing Prednisolone doses. Patients who ...
Abstract: Objective: Exercises, especially sports have an effective role in increasing of Bone Mineral Density (BMD). This study surveyed the bone density in athlete women compared to Iranian standard BMD at the same age and sex. Methods: This study was a prospective survey on thirty-nine athlete women between 20 to 30 years old. Subjects were selected randomly in six different athletes groups including basketball, volleyball, tennis, badminton, swimming and running. BMD was measured ...
Abstract: INTRODUCTION: There are six sets of diagnosis criteria for Behcet's Disease (BD). There is yet no general agreement on which one to use. The International criteria was created to bring this agreement. The aim of this study was to evaluate these criteria, especially the performance of the International criteria. MATERIALS and METHODS: Three countries (China, Iran and Korea) participated in the study. In each country, BD patients were selected as every ...
Abstract: Introduction: Posterior uveitis (PU) and retinal vasculitis (RV) are the main morbidity factor in Behcet’s Disease (BD). They usually progress toward severe loss of vision or blindness. They need aggressive treatment with cytotoxic drugs. Azathioprine was demonstrated, in a double blind control study, to be effective in Behcet’s Disease. The aim of this study was to evaluate the efficacy of Azathioprine in ocular lesions of BD, and to compare ...
Abstract: The bone mass density (BMD) may vary in different countries due to different genetic and environmental factors. This study was performed to determine the BMD of the normal population in Iran. Subjects were selected randomly from different social workers classes in Tehran (from the lowest to the highest). For each decade and sexes, 20 normal subjects were selected (140 men and 140 women). BMD was measured with a Hologic 1000 ...
Abstract: Introduction: Behcet's disease (BD) is a multisystem disease characterized by recurrent oral and genital ulcers, skin and ocular lesions. Other organ involvement occurs as minor manifestations of the disease. Cardiac involvement is not a common feature of the disease, but may be a sign for poor prognosis. The exact prevalence of cardiac involvement is not exactly known, only selected cases are reported in the literature. Our study .was designed to ...
Abstract: Introduction: Cytotoxic drugs are all effective in the treatment of ocular lesions of Behcet’s disease (BD). However, with all methods there are some patients that their eye lesions will progress despite the treatment. This study was designed to find whether a combination therapy with 2 of these drugs could have better effect in reducing the rate of non-responders. Materials & Methods: Twenty eight patients diagnosed as BD (according to the Iran ...
Abstract: Introduction: Behcet’s disease (BD) is not rare in children. Its clinical picture differs from adults. The purpose of this study was 1-To find the characteristics of juvenile BD (JBD). 2-To compare JBD with the adult from (ABD) of the disease. Materials & Methods: In a cohort of 3729 patients with BD, different manifestations of the disease, including 100 clinical and paraclinical data, were analyzed. Patients were divided in two groups. 1- ...
Abstract: The overlap syndrome is a vague entity in the group of connective tissue diseases. It is unclear whether it is fortuitous association of two or more connective tissue diseases (CTD), or a distinct disease. The early description of this syndrome was "a collection symptoms of CTD and the existence of anti - nRNP antibody". Many studies however, show that the anti - nRNP antibody is not specific for diagnosis. The ...
Abstract: Historical Background: Behcet's Disease (BD) is mainly seen along the Silk Rout This very peculiar geographical distribution arises the question that weather the disease was spread from east to west or from west to east. The epidemiology of BD in Iran shows that the genetic background is related to the East Asians (Mongoloid) race. This finding suggests that BD was spread along the Silk Route from East to ...