Abstract: Background: Cardiac involvement is not a common feature of Behcet's disease (BD), but may be a sign for poor prognosis. There are only few case reports in the literature and the prevalence of cardiac involvement in BD is not exactly known. Our study was designed to find the prevalence and characteristics of cardiac involvement in Iranian patients with BD. Methods: All new cases referred to Behcet's clinic ...
Abstract: Objectives: The ocular manifestations of Behcet's disease (BD) are very frequent involving approximately 60% of BD patients. These lesions consist mainly of uveitis (anterior, posterior, or panuveitis that are present in almost all the BD patients with ocular involvement) and necrotizing vasculitis of the retina. In a randomized survey carried on 1812 patients with Ocular-Behcet the prevalence of different ocular signs were as follow: Hypopion 8.7%, glaucoma 8.5%, cataract 70%, ...
Abstract: Introduction: The association of Behcet's disease (BD) and ankylosing spondylitis (AS) is still a controversial subject. As the presence of sacroiliac joint (SIJ) involvement is an essential criterion in the diagnosis of AS, we decided to determine the prevalence of SIJ involvement in BD and compare it with control group. Materials & Methods: We selected randomly 199 BD patients and 168 non-BD cases (CG), in a 12 month period (between April ...
Abstract: AIM and BACKGROUND: Osteoporosis is a health growing problem among senile .About 25 millions of people in the USA are suffering from osteoporosis who are dominantly women .The probability of women to men ratio is 5 to 1. There are more than 1.5 millions bone fractures because of osteoporosis that 300000 of them are at hip, 200000 at wrist and 500000 at vertebrae column. Hip fracture has the highest mortality ...
Abstract: Purpose: Cytotoxic drugs are the main therapeutic agents. A comparative study of 8 different therapeutic methods in 1220 cases is presented here. Materials & Methods: In an open, non-randomized control study, Pulse Cyclophosphamide (PCP), low dose PCP (LDP), oral cyclophosphamide ( OCP), weakly methotrexate ( MTX), chlorambucil ( CHL), cyclosporine A ( CYA), azathioprine (AZA), and combination therapy with LDP and MTX (COM) were used. Mean Duration: Ocular manifestations in months. FU: ...
Abstract: Background: In the literature, some of the skin pustular lesions of BD resembling the pustular lesion of acne vulgaris (AV) was called acneiform lesion of BD. It was suggested that AV was seen more often in BD than in normal population. AV is a common and very frequent skin lesion. The lesions are polymorphic, and are noninflamed (closed or open comedones) or inflamed (papules, pustules, nodules). Objectives: To find if ...
Abstract: Introduction: Despite the well-established association of malignancy and autoimmune diseases, malignancy seems to be infrequent in Behcet's Disease (BD). The evidence for neoplasm in BD is derived primarily from case reports (only 19 cases in the literature). This study was designed to find the occurrence of malignant disorders in a large group of patients with BD, and their characteristics. Patients & Methods: We reviewed the medical records of all patients with ...
Abstract: Introduction: Behcet's Disease (BD) is mainly seen in the countries along the Silk Rout. Among Asian countries, there is no data from Afghanistan on the clinical features of BD. Near 2 million Afghan immigrants live in Iran. This is a report on the clinical features of the disease in them with a comparison to the Iranian patients. Patients & Methods: All Afghan patients with BD referred to our BD unit ...
Abstract: Introduction: In a preliminary report to the 8th International Congress on Behcet’s Disease (BD) in 1998, we showed the efficacy of combination therapy with low dose pulse Cyclophosphamide (LDP) and Methotrexate (MTX) in posterior uveitis (PU) and retinal vasculitis (RV) of BD. We present here our experience with more patients and a longer follow up. Patients & Methods: BD Patients who were on the association of LDP and MTX due ...
Abstract: Purpose: Cardiac involvement is not a common feature of the scleroderma, but may be important. The aim of this study was to find the frequency and the characteristics of cardiac involvement in sclroderma. Methods: Our cases were selected consecutively from 1997 to 1999, according to the American College of Rheumatology criteria. A complete cardiac examination (clinical, electrocardiography, chest X-ray, echocardiography, exercise test) was performed for all patients. These data were ...